Letter: Intermittent claudication complicating beta-blockade.
نویسندگان
چکیده
منابع مشابه
Intermittent claudication complicating beta-blockade.
Intermittent claudication is an occasional side effect of beta-adrenergic blockade' but clinical details are lacking. Beta-blocking agents may exacerbate intermittent claudication in patients with severe peripheral arterial insufficiency.2 The following cases suggest that they may also provoke claudication in patients with previouslv asymptomatic peripheral arterial disease. Case 1 A man aged 5...
متن کاملbeta blockade and intermittent claudication: placebo controlled trial of atenolol and nifedipine and their combination.
OBJECTIVE To determine the effects of the beta 1 selective adrenoceptor blocker atenolol, the dihydropyridine calcium antagonist nifedipine, and the combination of atenolol plus nifedipine on objective and subjective measures of walking performance and foot temperature in patients with intermittent claudication. DESIGN Randomised controlled double blind four way crossover trial. SETTING Roy...
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Peripheral arterial disease is a common health problem that globally affects over 200 million individuals, and intermittent claudication (IC) is the most common symptomatic presentation. The leg symptoms in IC are provoked by walking exercise and can be alleviated by medical intervention, exercise training and invasive vascular interventions (revascularization). The quality of evidence for inva...
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To clarify contradictions in past reports and the package inserts for beta-adrenergic blocking agents (beta-blockers) for patients with intermittent claudication (IC), we investigated the effects of beta-blockers in patients with IC using the systematic review technique. Data sources were randomized, controlled trials that investigated the effects of beta-blockers compared with the placebo or u...
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Increased blood viscosity has been shown to be an important factor in reducing blood flow in a review and analysis of the history, clinical findings, and haemodynamic, rheological, radiological, and biochemical measurements in 126 patients with intermittent claudication. In some patients increased viscosity seemed to be the determining cause of claudication. A raised plasma fibrinogen was the m...
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ژورنال
عنوان ژورنال: BMJ
سال: 1976
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.6023.1469-d